Ann Arbor,  MI 
United States
  • 1022

Genomenon, Home of the Mastermind Genomic Search Engine


Genomenon provides immediate insight into the published genomic research for every disease, gene, and variant found in the scientific literature. The Mastermind Genomic Search Engine has the world’s largest collection of medical articles cataloguing genetic relationships between DNA and human diseases, including cancer. 


Used by hundreds of diagnostic labs around the world, Mastermind accelerates genomic interpretation by providing unique insight into the “Genomic Associations” found in the full text of millions of scientific articles. These associations help clinical labs more accurately and rapidly diagnose patients. Each added component of association data increases the ability of Mastermind users to find genetic evidence, test or generate hypotheses, and draw clinical conclusions with confidence.


Genomenon was named 2020 Global Company of the Year in Clinical Genomics Interpretation by Frost & Sullivan. Below is an excerpt from their analysis:


Mastermind accelerates tertiary analysis by identifying every research article that includes any given variant in the context of any disease or phenotype and prioritizes the search results by clinical relevance. It leverages artificial intelligence (AI) and machine learning (ML) to offer the world’s most comprehensive gene and variant landscape, having indexed 100 times more content and identified 20 times more variants than the incumbent database built by manual curation. It also reduces the average 90-minute variant search and curation time using Google or Google Scholar to less than 30 minutes, delivering industry-leading turnaround times and superior diagnostic yields and throughput.


“Powered by its proprietary Genomic Language Processing™ algorithm and genomic literature database, Mastermind has emerged a leading automated disease-gene-variant association database,” said Christi Bird, Principal Consultant at Frost & Sullivan. “Unlike other commercially available tools, the first-in-class genomic database search engine enables full articles and supplemental datasets searches across the genomic literature—allowing geneticists, molecular pathologists, and researchers to identify disease-causing variants from genomic-sequencing datasets quickly and accurately.”