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Charles Sadle

Charles Sadle

Child Neurology Resident Physician, University of Louisville

Dr. Sadle is in his final year of child neurology fellowship at University of Louisville in Louisville, KY. Next year he plans on beginning a genetics fellowship to learn the skills necessary to practice as a Pediatric Neurogenetecist in the service of children with Autism and Developmental Disabilities. Under the mentorship of Dr. Andrea Gropman he has co-authored a book chapter "Epigenetics of Autism Spectrum Disorder"which will be published with the next edition of Epigenetics of Psychiatry. He has a particular interest in the gut microbiome and the oxytocin system as they relate to inflammatory stress signaling in Autism. His research interests involve understanding how the stress and inflammatory axis predisposes children to develop Autism, with the goal of reducing Autism prevalence through identification of patient subgroups and stress/inflammatory biomarkers that correlate with autism severity scores.