University of Toronto
Dr. Malkin is Professor of Pediatrics and Medical Biophysics in the Faculty of Medicine, University of Toronto. He holds the CIBC Children's Foundation Chair in Child Health Research, is a Staff Oncologist in the Division of Hematology/Oncology, Director of the Cancer Genetics program, and a Senior Scientist in the Genetics and Genome Biology Program at The Hospital for Sick Children in Toronto. Dr. Malkin co-leads the SickKids Precision Child Health initiative. He co-directs the SickKids Cancer Sequencing (KiCS) program which integrates next generation sequencing (NGS) into clinical care of children with cancer, and Director of the pan-Canadian PRecision Oncology For Young peopLE (PROFYLE) initiative which is establishing a pipeline to incorporate NGS into novel clinical trials for children and young adults with hard-to-cure cancers across Canada. Dr. Malkin's research focuses on genetic mechanisms of childhood cancer susceptibility particularly in the context of TP53 and Li-Fraumeni syndrome. Recently, his work has addressed the application of genomics to clinical surveillance and treatment approaches for children and adults at genetic 'high risk' for cancer.