Dr. Biesecker is a Distinguished Investigator, and Director of the Center for Precision Health Research at the National Human Genome Research Institute of the National Institutes of Health, which he joined in 1993. He uses genetic and genomic technologies to study the etiology of genetic disorders and has published over 300 primary research articles, reviews, and chapters and developed the ClinSeq® program, which began clinical genomics research in 2006, before the widespread availability of next generation sequencing. He is double board certified in Pediatrics and Medical Genetics. He was elected to the National Academy of Medicine of the National Academy of Science in 2018 and was the President of the American Society of Human Genetics for 2019.