Marlen Lauffer, MD is a senior researcher at the Dutch Center for RNA Therapeutics (DCRT). She has a background in biochemistry, human molecular genetics, and medicine, and has been studying rare diseases in and outside of the wet lab for the past decade. Marlen is especially interested in rare neurological disorders manifesting in childhood, like neurodevelopmental disorders and childhood dementias. At the DCRT, Marlen is responsible for patient evaluation and identifying amenable genetic variants for N=1+ treatments as well as overseeing the development and testing of antisense oligonucleotides in the wet lab. She is co-leading the N=1 Collaborative Patient Identification Working Group.