Dr. Sharon Plon is a board-certified medical geneticist and a longstanding cancer genetics researcher including leading to the discovery of new cancer susceptibility genes and the implementation of genomic testing in medicine. Dr. Plon holds the Dan L Duncan Comprehensive Cancer Center Professorship at Baylor College of Medicine in the Departments of Pediatrics/Hematology-Oncology, Molecular and Human Genetics and Human Genome Sequencing Center. Dr. Plon serves as PI with Donald (Will) Parsons and Amy McGuire on the NHGRI/NCI- U01 Texas KidsCanSeq multi-institutional trial that studies the incorporation of CLIA clinical genome-scale exome sequencing into the care of childhood cancer patients in the diverse patient populations in Texas. Since 2013, Dr. Plon has served as one of the Principal Investigators of the Clinical Genome (ClinGen) Resource and co-chairs the ClinGen hereditary cancer effort. She also currently co-chairs the germline reporting effort of the national NCI/COG Pediatric MATCH Precision Oncology trial.