
Shawn McCandless
Professor,
Children's Hospital Colorado
Shawn E. McCandless, MD, is Professor of Pediatrics, and the Section Head for Genetics and Metabolism at the University of Colorado Anschutz Medical Campus and Chair of the Department of Genetics and Metabolism at Children's Hospital Colorado. His research and clinical care focus on inborn errors of metabolism (IEM) and Prader-Willi syndrome (PWS), including publicly and industry funded clinical trials for children and adults with IEMs and PWS. He is currently involved in a variety of clinical trials, including gene therapy trials for OTCD and GSD1a, several small molecule approaches for treatment of PWS and genetic obesity. He is the Clinical Team Liaison for the Urea Cycle Disorders Consortium (UCDC) of the NIH Rare Diseases Clinical Research Network and serves as the chair of the Industry Relations Committee (IRC), having been a member of the UCDC since 2008. He is a founding member of the Prader-Willi Syndrome Clinical Investigation Collaborative (PWS-CLIC), where he also chairs the IRC. He is a Past President of the Society for Inherited Metabolic Disorders (SIMD). He has served as a member of the Advisory Committee on Heritable Disorders of Newborns and Children (HRSA) and he is the Chair of the Colorado Rare Diseases Advisory Council. He has served a consultant for a variety of industry partners as a content expert and for clinical trial design. Previous employment includes working as a general pediatrician at the Northern Navajo Medical Center in Shiprock, NM, and faculty positions in Genetics and Metabolism at the University of North Carolina – Chapel Hill, and Case Western Reserve University, prior to moving to Colorado in 2018.
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