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Theodore Drivas

Theodore Drivas

Assistant Professor, University of Pennsylvania
Teddy completed MD-PhD training in Cell and Molecular Biology at the University of Pennsylvania where his doctoral work in the lab of Dr. Jean Bennett focused on understanding the molecular mechanisms underlying a group of fascinating and devastating genetic disorders known as the ciliopathies. Inspired by the bravery and altruism of these rare disease patients, Teddy pursued clinical residency training in Internal Medicine at Columbia and in Medical Genetics at the Children's Hospital of Philadelphia to provide better clinical care and a deeper scientific understanding for patients living with rare genetic conditions. He came back to the Penn to complete postdoctoral training with Dr. Marylyn Ritchie where his work focused on using informatic approaches to understand how the same genes that cause rare genetic disorders can also play a role in the pathogenesis of common complex disease in the general population. Teddy opened his own lab at Penn in January of 2023. The overarching goal of his research is to understand the intersection of common and rare disease genetics to uncover the genetic architecture and molecular mechanisms of human disease. His team takes a conceptually innovative approach to their research, bridging genomics and classic genetics, integrating informatic, molecular, translational, and clinical approaches, to investigate their hypotheses and perform their work. While the lab has a particular focus on disorders affecting the primary cilium, their science is guided by genetic discovery and they are excited to tackle interesting questions agnostic of organ system or disease pathogenesis.