Youbao Sha, PhD, FACMG Lab Director Natera Clinical Molecular Genetics and Genomics; Clinical Cytogenetics and Genomics

13 Mar 2026
Molecular Genetics

Dr. Youbao Sha is a board-certified in Clinical Molecular Genetics and Genomics and cytogenetics and genomics. Dr. Sha is a Laboratory Director at Natera, where he oversees high-complexity clinical genetic testing with a focus on reproductive, prenatal, and hereditary cancer diagnostics. He has extensive expertise in germline testing, whole-exome sequencing, RNA-based variant interpretation, cell-free DNA testing, and preimplantation genetic testing. His research interests include integrating RNA and DNA sequencing to refine variant classification, advancing paired tumor–germline testing strategies, and improving diagnostic yield in prenatal and reproductive genetics. Dr. Sha has authored many peer-reviewed publications spanning clinical genomics, cancer genetics, and molecular mechanisms of disease, and he is actively involved in laboratory quality assurance, assay development, and mentoring early-career geneticists.